Cloned (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine | - |
Bos taurus | |
ATP | - |
Bos taurus | |
Wortmannin | type II enzyme is inhibited by low concentrations, type III enzyme requires mM concentrations for inhibition | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
chromaffin granule | - |
Bos taurus | 42583 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
membrane | type II enzyme is almost exclusively found in membrane fraction | Bos taurus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
54305 | - |
x * 54305, calculation from nucleotide sequence | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | Rattus norvegicus | - |
ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol | Bos taurus | phosphorylation of phosphatidylinositol at the D-4 position is an essential step in the biosynthesis of phosphatidylinositolpolyphosphates | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | PI4KII and PI4KIII | Bos taurus | - |
brain | - |
Rattus norvegicus | - |
brain | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | - |
Rattus norvegicus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol | - |
Bos taurus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol | phosphorylation of phosphatidylinositol at the D-4 position is an essential step in the biosynthesis of phosphatidylinositolpolyphosphates | Bos taurus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | - |
Rattus norvegicus |
? | x * 54305, calculation from nucleotide sequence | Bos taurus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.045 | - |
adenosine | type II enzyme | Bos taurus | |
0.088 | - |
ATP | type II enzyme | Bos taurus |